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Protein Coding Gene : Pnliprp1 pancreatic lipase related protein 1

Primary Identifier  MGI:97723 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  18946
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable lipase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and respiratory system. Orthologous to human PNLIPRP1 (pancreatic lipase related protein 1).
PHENOTYPE: Mice homozygous for a knock-out allele show increased lipase activity in pancreatic juice and develop obesity associated with increased body fat mass, impaired glucose tolerance and insulin resistance, with these conditions exacerbated on a high-fat diet. [provided by MGI curators]
  • synonyms:
  • pancreatic lipase related protein 1,
  • Plrp1,
  • MGD-MRK-13545,
  • Pnliprp1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For