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Publication : Expression of H-2K and H-2D genes by PYS-2 teratocarcinoma cells.

First Author  Nagata T Year  1988
Journal  Biochem Biophys Res Commun Volume  157
Issue  2 Pages  648-56
PubMed ID  3202874 Mgi Jnum  J:118709
Mgi Id  MGI:3700195 Doi  10.1016/s0006-291x(88)80299-7
Citation  Nagata T, et al. (1988) Expression of H-2K and H-2D genes by PYS-2 teratocarcinoma cells. Biochem Biophys Res Commun 157(2):648-56
abstractText  The parietal yolk-sac carcinoma cell line PYS-2, which has been described to synthesize a trace amount of H-2 antigens, was shown to express low levels of Kb- and/or Db-specific antigens by flow cytometric analysis. Further studies of H-2 cDNA clones from PYS-2 cDNA library revealed 8 out of 10 clones were identified as classical H-2Kb and 2 were H-2Db, which confirmed the result from the immunofluorescent analysis. However, we have not isolated Qa, Tla or other embryonic class I cDNAs from our PYS-2 library.
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