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Publication : Molecular cloning of mouse alpha-1,6-fucosyltransferase and expression of its mRNA in the developing cerebrum.

First Author  Hayashi H Year  2000
Journal  DNA Seq Volume  11
Issue  1-2 Pages  91-6
PubMed ID  10902914 Mgi Jnum  J:74082
Mgi Id  MGI:2157612 Doi  10.3109/10425170009033974
Citation  Hayashi H, et al. (2000) Molecular cloning of mouse alpha-1,6-fucosyltransferase and expression of its mRNA in the developing cerebrum. DNA Seq 11(1-2):91-6
abstractText  Complementary DNA encoding mouse alpha-1,6-fucosyltransferase (FUT) was cloned. The deduced primary structure consisted of 575 amino acids and had 96.0% and 93.0% identity with alpha-1,6-FUT of human and porcine origin, respectively. Quantitative analysis of alpha-1,6-FUT mRNA expression during selected developmental stages of the cerebrum showed that the expression increased during later embryonic stages and was highest in the early postnatal stages (P1 to P7), after which it declined somewhat but still remained relatively high in the mature adult. The expression profile suggests important roles of FUT in the developing central nervous system.
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