| First Author | Fong D | Year | 1992 |
| Journal | Hum Genet | Volume | 89 |
| Issue | 1 | Pages | 10-2 |
| PubMed ID | 1577456 | Mgi Jnum | J:889 |
| Mgi Id | MGI:49421 | Doi | 10.1007/BF00207033 |
| Citation | Fong D, et al. (1992) Confirmation of the human cathepsin B gene (CTSB) assignment to chromosome 8. Hum Genet 89(1):10-2 |
| abstractText | Human cathepsin B gene (CTSB) has been mapped to two locations: 8p22 and 13q14. Here we confirm the chromosome 8 assignment by three independent methods: (1) analysis of human-hamster somatic cell hybrid DNA by polymerase chain reaction; (2) comparison of hybridization signals to cathepsin B in interphase nuclei of normal fibroblasts and fibroblasts with a chromosome 8 deletion; and (3) fluorescence in situ hybridization to metaphase spreads using cathepsin B cosmid clones. Our results indicate that human CTSB is located at 8p22-p23.1. |
