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Allele : Nr1h2<tm1Djm> nuclear receptor subfamily 1, group H, member 2; targeted mutation 1, David J Mangelsdorf

Primary Identifier  MGI:3041856 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nr1h2
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of a targeting vector replaced exons 5 and 6 with a neomycin resistance cassette creating a null allele. Exons 5 and 6 encode the DNA-binding and ligand-binding domains.
  • mutations:
  • Insertion
  • synonyms:
  • LXRbeta<->,
  • LXRbeta<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

93 Publication categories

Trail: Allele