|  Help  |  About  |  Contact Us

Protein Domain : Solute carrier family 26 member 8 (testis anion transporter 1)

Primary Identifier  IPR030303 Type  Family
Short Name  SLC26A8
description  The testis anion transporter TAT1 (solute carrier family 26 member 8; SLC26A8) mediates chloride, sulfate and oxalate transport and is specifically expressed in male germ cells and mature sperms [, ]. It is essential for correct sperm tail differentiation and motility, and hence male fertility []. TAT1 and CFTR (cystic fibrosis transmembrane conductance regulator) seem to cooperate in the regulation of the Cl-/HCO3- fluxes required for motility and capacitation of sperm [].

0 Child Features

1 Parent Features

5 Protein Domain Regions