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Protein Coding Gene : Tab3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
Primary Identifier  MGI:1913974 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  66724
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity; molecular adaptor activity; and zinc ion binding activity. Predicted to be involved in defense response to bacterium; non-canonical NF-kappaB signal transduction; and positive regulation of canonical NF-kappaB signal transduction. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including adrenal gland; gonad; liver; lung; and spleen. Orthologous to human TAB3 (TGF-beta activated kinase 1 (MAP3K7) binding protein 3).
PHENOTYPE: Male chimeras hemizygous for a gene trapped allele appear normal at E9.5. [provided by MGI curators]
  • synonyms:
  • TGF-beta activated kinase 1/MAP3K7 binding protein 3,
  • Tab3,
  • 4921526G09Rik,
  • RIKEN cDNA 4921526G09 gene,
  • Map3k7ip3,
  • mitogen-activated protein kinase kinase kinase 7 interacting protein 3
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