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Protein Coding Gene : Gnai3 G protein subunit alpha i3

Primary Identifier  MGI:95773 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  14679
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including G-protein beta/gamma-subunit complex binding activity; GDP binding activity; and GTPase activating protein binding activity. Predicted to be involved in several processes, including GTP metabolic process; positive regulation of superoxide anion generation; and positive regulation of vascular associated smooth muscle cell proliferation. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Located in Golgi apparatus. Is expressed in early conceptus; inner ear; and oocyte. Orthologous to human GNAI3 (G protein subunit alpha i3).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal basal cardiac function and beta-adrenergic sensitivity. Mice homozygous for a different knock-out allele exhibit enhanced T cell migration toward CXCR3 agonists. [provided by MGI curators]
  • synonyms:
  • AI158965,
  • expressed sequence AI158965,
  • MGD-MRK-10182,
  • guanine nucleotide binding protein (G protein), alpha inhibiting 3,
  • G protein subunit alpha i3,
  • Galphai3,
  • MGI:2139639,
  • Gnai3,
  • MGD-MRK-10185,
  • expressed sequence AW537698,
  • AW537698,
  • MGI:2139991,
  • Gnai-3

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

20 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For