Primary Identifier | MGI:2652846 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 241118 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable ligand-gated sodium channel activity. Acts upstream of or within behavioral fear response. Predicted to be located in membrane. Is expressed in several structures, including adrenal gland; brain; gut; male reproductive gland or organ; and spinal cord mantle layer. Orthologous to human ASIC4 (acid sensing ion channel subunit family member 4). PHENOTYPE: Homozygous knockout increases the fear response in the predator-odor induced fear test and increases anxiety in open field and elevated plus maze tests. [provided by MGI curators] |