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Publication : cDNA cloning and mRNA expression of Transformer 2 (Tra 2) in chicken embryo.

First Author  Yamamoto I Year  2002
Journal  Biochim Biophys Acta Volume  1579
Issue  2-3 Pages  185-8
PubMed ID  12427554 Mgi Jnum  J:80462
Mgi Id  MGI:2445897 Doi  10.1016/s0167-4781(02)00511-0
Citation  Yamamoto I, et al. (2002) cDNA cloning and mRNA expression of Transformer 2 (Tra 2) in chicken embryo. Biochim Biophys Acta 1579(2-3):185-8
abstractText  We report the cloning of a chicken Transformer 2 (Tra 2) cDNA that encodes a protein of 289 amino acids which are 97.9% identical to those of mammalian splicing factor, Tra 2. Tra 2 mRNA was expressed in chicken embryonic tissues and was observed as a band of 1.5 kb by Northern blot analysis. Whole mount in situ hybridization showed an mRNA expression of Tra 2 in telencephalon, mandible, hyoid arch, wing and leg buds as early as day 3.5 of incubation. These results suggest that the Tra 2 gene may play a role in organogenesis in the chicken embryo.
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