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Allele : Lipe<tm1Rze> lipase, hormone sensitive; targeted mutation 1, Rudolf Zechner
Primary Identifier  MGI:2388334 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lipe
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin selection cassette was inserted in intron 1 and an additional loxP site was inserted 3' to exon 7. The resulting targeted ES cells were subjected to transient cre expression. Exons 2 to 7 as well as neomycin selection cassette were deleted. In addition to this allele, transient expression provided recombinant ES cells in which only the selection cassette was deleted. These cells were used to produce Lipetm2Rze.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • HSL<->,
  • HSL<->,
  • HSL-ko,
  • HSL-ko
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

20 Publication categories

Trail: Allele




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