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Protein Domain : Deubiquitinating protein VCPIP1

Primary Identifier  IPR039087 Type  Family
Short Name  VCPIP1
description  VCPIP1, also known as VCIP135, is a deubiquitinating enzyme that functions in p97/p47-mediated Golgi reassembly []. It hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains []. It has also been found to dictate the duration of botulinum neurotoxin type A intoxication []. VCPIP1 can also deubiquitinate SPRTN (a metalloprotease that cleaves DNA-protein crosslinks) and promotes its chromatin relocalization []. VCPIP1 is a member of peptidase family C64.

0 Child Features

0 Parent Features

5 Protein Domain Regions