Primary Identifier | IPR039087 | Type | Family |
Short Name | VCPIP1 |
description | VCPIP1, also known as VCIP135, is a deubiquitinating enzyme that functions in p97/p47-mediated Golgi reassembly []. It hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains []. It has also been found to dictate the duration of botulinum neurotoxin type A intoxication []. VCPIP1 can also deubiquitinate SPRTN (a metalloprotease that cleaves DNA-protein crosslinks) and promotes its chromatin relocalization []. VCPIP1 is a member of peptidase family C64. |