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Publication : Expression of gamma-adducin is associated with regions of morphogenetic cell movement in the chick embryo.

First Author  Akai J Year  2002
Journal  Mech Dev Volume  119 Suppl 1
Pages  S191-5 PubMed ID  14516684
Mgi Jnum  J:82201 Mgi Id  MGI:2651759
Doi  10.1016/s0925-4773(03)00115-1 Citation  Akai J, et al. (2002) Expression of gamma-adducin is associated with regions of morphogenetic cell movement in the chick embryo. Mech Dev 119 Suppl 1:S191-5
abstractText  The adducin family of cytoskeletal proteins are known to mediate actin driven cell movements. Here we describe the cloning and expression pattern of a gene encoding gamma-adducin in the chick embryo. Expression of this gene is strikingly restricted to the epithelial cell layer (with a few exceptions including emerging notochord and lateral mesoderm). Gamma-adducin is detected at particularly high levels in cell populations undergoing important morphogenetic movements, such as epiblast approaching the primitive streak, regressing spinal cord primordia and closing neural tube.
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