| Primary Identifier | MGI:2450300 | Allele Type | Transgenic |
| Attribute String | No functional change, Recombinase | Gene | Plekha5 |
| Strain of Origin | (C57BL/6 x SJL)F1 | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | The transgene consists of a human AMH promoter, a cre recombinase gene, and genomic sequences from MT1 to provide mRNA secondary structure stability. The gene trap inserted into intron 3. Northern blot analysis shows gonad-specific transgene expression in Sertoli cells of 6 day old male mice and granulosa cells of 16 day old female mice. RT-PCR confirmed normal endogenous gene expression. The insertion site of the original cre transgene was subsequenly identified as intron 3 of Plekha5. |
