| Primary Identifier | IPR027182 | Type | Family |
| Short Name | TLR10 |
| description | Toll-like receptor 10 (TLR10) participates in the innate immune response to microbial agents. The human TLR family consist of numerous members, which recognise a wide variety of pathogen-associated molecular patterns. No ligand has yet been reported for TLR10, thus it remains the only orphanfamily member []. It acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. TLR10 has been shown to form homodimers and to interact with TLRs 1 and 2 []. |
