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Protein Coding Gene : Stk3 serine/threonine kinase 3

Primary Identifier  MGI:1928487 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  56274
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including ATP binding activity; identical protein binding activity; and magnesium ion binding activity. Involved in hippo signaling. Acts upstream of or within several processes, including chordate embryonic development; hepatocyte apoptotic process; and regulation of signal transduction. Located in cytoplasm. Is expressed in female associated reproductive structure; lung; male associated reproductive structure; and renal vasculature. Orthologous to human STK3 (serine/threonine kinase 3).
PHENOTYPE: Homozygous inactivation of this gene generally results in mice that are viable, fertile and developmentally normal. A small subset of mice homozygous for a knock-out allele develop mammary tumors in the absence of immunological defects. [provided by MGI curators]
  • synonyms:
  • mess1,
  • RIKEN cDNA 0610042I06 gene,
  • MGI:1914102,
  • serine/threonine kinase 3,
  • MST,
  • Ste20,
  • 0610042I06Rik,
  • Mst2,
  • Stk3

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For