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Protein Coding Gene : Dusp4 dual specificity phosphatase 4
Primary Identifier  MGI:2442191 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  319520
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable phosphoprotein phosphatase activity. Predicted to be involved in endoderm formation and negative regulation of ERK1 and ERK2 cascade. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in nervous system; olfactory epithelium; and unsegmented mesenchyme. Orthologous to human DUSP4 (dual specificity phosphatase 4).
PHENOTYPE: Mice homozygous for a null allele exhibit a decrease in B cell apoptosis of bone marrow-derived, IL-7-dependent pro-B lymphocytes. [provided by MGI curators]
  • synonyms:
  • dual specificity phosphatase 4,
  • MGI:2142625,
  • BB104621,
  • MKP2,
  • MGI:1917486,
  • E130306H24Rik,
  • AI844617,
  • RIKEN cDNA E130306H24 gene,
  • RIKEN cDNA 2700078F24 gene,
  • 2700078F24Rik,
  • expressed sequence BB104621,
  • Dusp4,
  • expressed sequence AI844617,
  • MGI:2142829
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Trail: ProteinCodingGene




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