| Primary Identifier | MGI:99678 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 11474 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables actin filament binding activity. Involved in several processes, including positive regulation of skeletal muscle tissue development; regulation of generation of precursor metabolites and energy; and regulation of muscle system process. Located in Z disc and brush border. Is expressed in several structures, including autopod; skeletal musculature; testis; trunk myotome; and upper jaw incisor. Orthologous to human ACTN3 (actinin alpha 3). PHENOTYPE: Mice homozygous for a null allele exhibit an increase mitochondria density and a shift from anaerobic to aerobic metabolism in fast muscle fiber that is associated with increased aerobic capacity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
