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Allele : Csnk1e<tm1Asil> casein kinase 1, epsilon; targeted mutation 1, Andrew S I Loudon

Primary Identifier  MGI:3793318 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Csnk1e
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo cassette was inserted downstream of a modified exon 4 containing a C to T transition at base pair 12555 (C12555T) and an additional loxP site was inserted upstream of the modified exon 4. The neo cassette was removed by germ line, cre-mediated recombination that left the modified exon 4 floxed. The transition mimics a gain of function mutation identified in hamsters as having a destabilizing effect on Per1.
  • mutations:
  • Single point mutation
  • synonyms:
  • CK1epsilon<tau>,
  • CK1epsilon<tau>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

14 Publication categories

Trail: Allele