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Allele : Igsf1<tm1Zuk> immunoglobulin superfamily, member 1; targeted mutation 1, Martin M Matzuk

Primary Identifier  MGI:2671049 Allele Type  Targeted
Attribute String  Null/knockout Gene  Igsf1
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 1 was replaced with a PGK-HPRT cassette. This deletes the transcription start site used by three isoforms of this gene. Northern blot analysis indicated that mRNA for these isoforms was not present. mRNA for a fourth isoform which uses a different transcription start site was detectable however. These results were confirmed by RT-PCR.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Igsf1<deltaexon1>,
  • Igsf1<deltaexon1>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele