Primary Identifier | MGI:2444228 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 219158 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables enzyme inhibitor activity. Involved in regulation of circadian rhythm. Predicted to be located in mitochondrial matrix; nucleoplasm; and spindle. Predicted to be part of DBIRD complex and chromatin. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system and retina. Orthologous to human CCAR2 (cell cycle and apoptosis regulator 2). PHENOTYPE: Homozygous null mice on a high fat diet are resistant to hepatic steatosis and associated liver inflammation. [provided by MGI curators] |