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Allele : Rr124128<tm1.2Jfer> regulatory region 124128; targeted mutation 1.2, Jorge Ferrer
Primary Identifier  MGI:7431276 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout Gene  Rr124128
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT site flanked neomycin resistance gene cassette and a loxP site were inserted upstream of the Hnf1aos1 gene promoter/1st exon and a second loxP site downstream of the Hnf1aos2 gene promoter/1st exon. These exons, promoters and loxP sites are located in Hnf1a intron 1. The neo cassette was removed through subsequent flp-mediated recombination. The ~1.8 kb floxed sequence, containing Hnf1aos1 and Hnf1aos2 promoters and 1st exons, was subsequently deleted through cre-mediated recombination.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Haster<->,
  • Haster<->
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1 Feature

Trail: Allele

Genome

0 Expresses

2 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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