Primary Identifier | MGI:6331300 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inducible, Inserted expressed sequence, Reporter | Gene | Tg(tetO-GFP,-APOL1*)#Susz |
Strain of Origin | FVB/N | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The human APOL1 kidney disease risk variant G1, that has a six nucleotide deletion and is able to lyse T. brucei rhodesiense, is under the control of the tetracycline responsive promoter element. The pound (#) sign is used when the line number is not specified or lines are pooled. The gene is only expressed in a tetracycline/doxycycline controllable manner when mice carrying this allele also carry a tTA or rtTA allele. |