Primary Identifier | MGI:1914928 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 67678 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable U6 snRNA 3'-end binding activity. Predicted to be involved in P-body assembly and mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of Lsm1-7-Pat1 complex; Lsm2-8 complex; and nucleus. Predicted to be active in P-body. Is expressed in central nervous system and sensory organ. Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated). PHENOTYPE: MIce homozygous for an allele that only expresses variant 1 exhibit decreased susceptibility to VSV and influenza infection. [provided by MGI curators] |