Primary Identifier | IPR044403 | Type | Domain |
Short Name | PRDM10_PR/SET |
description | This entry represents the PR/SET domain found in PR domain zinc finger protein 10 (PRDM10). PRDM10 may be involved in transcriptional regulation [, , ].The PRDM family members are characterised by the presence of a N-terminal PR (PRDI-BF1 and RIZ1 homology) domain followed by multiple zinc fingers which confer DNA binding activity. PR domains are only distantly related to the classical SET methyltransferase domains []. They are involved in epigenetic regulation of gene expression through their intrinsic histone methyltransferase activity or via interactions with other chromatin modifying enzymes []. |