Type | MGI:General | Description | less islets (60-65%) display infiltrating mononuclear cells than Tnf-transgenic mice from F1 crosses to NOD mice (seen in 100% of animals) at 5 months of age in prediabetic mice, CD4+ and CD8+ T cells represent 50% of infiltrating cells in islets; the other 50% are CD4/CD8 double negative cells |