Primary Identifier | MGI:5751809 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Schip1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 10 and a floxed EGFP/hygro cassette was inserted downstream of exon 11 via homologous recombination. Cre mediated recombination removed exon 10 and the EGFP/hygro cassette. Immunoblot analysis revealed the absence of both all wild-type isoforms and any truncated proteins in homozygous mutant mice. |