Primary Identifier | IPR042762 | Type | Domain |
Short Name | PKHF1_FYVE |
description | Pleckstrin homology domain-containing family F member 1 (PKHF1), also known as Phafin-1, is a representative of a novel family of PH and FYVE domain-containing proteins called phafins. It is a ubiquitously expressed pro-apoptotic protein via translocating to lysosomes, facilitating apoptosis induction through a lysosomal-mitochondrial apoptotic pathway []. |