Primary Identifier | MGI:5543772 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Ehmt1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Most of the reading frame was replaced by a loxP site, cDNA with a nucleotide substitution results in the amino acid substitution of alanine for cysteine at position 1201 (C1201A) in the methyltransferase-dead SET-domain, IRES, neomycin resistance cassette and a loxP site. The mutation abolishes enzymatic activity but does not affect heterodimerization with Ehmt2. |