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Allele : Ehmt1<tm2Yshk> euchromatic histone methyltransferase 1; targeted mutation 2, Yoichi Shinkai

Primary Identifier  MGI:5543772 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Ehmt1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Most of the reading frame was replaced by a loxP site, cDNA with a nucleotide substitution results in the amino acid substitution of alanine for cysteine at position 1201 (C1201A) in the methyltransferase-dead SET-domain, IRES, neomycin resistance cassette and a loxP site. The mutation abolishes enzymatic activity but does not affect heterodimerization with Ehmt2.
  • mutations:
  • Single point mutation,
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • GLP<CA>,
  • GLP<flox>,
  • GLP<flox>,
  • GLP<CA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele