Primary Identifier | IPR029327 | Type | Family |
Short Name | HAUS4 |
description | HAUS4 is part of the HAUS augmin-like complex, which contributes to mitotic spindle assembly, maintenance of chromosome integrity and completion of cytokinesis [, ].Human augmin complex is composed of 8 subunits and interacts with the gamma-tubulin ring complex (gamma-TuRC) in centrosomes []. This interaction affects MT generation during mitosis and is critical for chromosome segregation and cytokinesis in human cells []. Similar to humans, Arabidopsis augmin complex also contains 8 subunits, including AUGMIN subunit 4 (AUG4) in this entry []. Despite lacking cetrosomes, the augmin complex in Arabidopsis also plays an important part in gamma-tubulin-dependent MT nucleation and the assembly of microtubule arrays during mitosis []. |