| Primary Identifier | MGI:2429736 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Il2rg |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = E14.1 (129P2/OlaHsd) or EK.CCE (129S/SvEv-Gpi1c). |
| molecularNote | A sequence fragment containing portions of exon 7 and 8 was replaced with a neo cassette inserted by homologous recombination. The deleted region encoded the majority of the SH2-like domain. Flow cytometry and the use of labeled thymidine indicated that the mutant protein localized to the surface of thymocytes but did not transduce signals. |
