Primary Identifier | MGI:1858230 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 53890 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable histone binding activity; snRNA binding activity; and ubiquitin-specific protease binding activity. Acts upstream of or within cell morphogenesis; hematopoietic stem cell proliferation; and homeostasis of number of cells. Located in Cajal body. Is expressed in several structures, including blastocyst; central nervous system; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human SART3 (spliceosome associated factor 3, U4/U6 recycling protein). PHENOTYPE: Mice homozygous for a conditional allele activated in hematopoietic cells exhibit protection against the effects of 5-FU treatment. [provided by MGI curators] |