Primary Identifier | MGI:3826433 | Allele Type | Targeted |
Attribute String | Conditional ready, Hypomorph | Gene | Pkd2 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neo cassette flanked by two FRT sites was inserted upstream of exon 3 and two loxP sites were inserted to flank exon 3. Reduced protein expression was confirmed by western blot analysis on kidney extracts. This allele is hypomorphic. |