Primary Identifier | MGI:3590649 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Dkk2 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance gene replaced the four coding exons via homologous recombination. RT-PCR failed to detect transcript in mutant bone marrow stromal osteoblasts, and western blot confirmed absence of protein in mutants. |