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Protein Domain : Deleted in lung and esophageal cancer protein 1

Primary Identifier  IPR033304 Type  Family
Short Name  DLEC1
description  Deleted in lung and esophageal cancer (DLEC1) is a tumour suppressor that is frequently silenced by promoter methylation in various kinds of cancer [, , ]. However, in head and neck squamous cell carcinoma, DLEC1 is not silenced solely by promoter methylation []. It has been shown to repress NF-kB signalling in prostate cancer [].

0 Child Features

0 Parent Features

4 Protein Domain Regions