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Publication : The mouse gap junction gene connexin29 is highly expressed in sciatic nerve and regulated during brain development.

First Author  Söhl G Year  2001
Journal  Biol Chem Volume  382
Issue  6 Pages  973-8
PubMed ID  11501764 Mgi Jnum  J:70957
Mgi Id  MGI:2148729 Doi  10.1515/BC.2001.122
Citation  Sohl G, et al. (2001) The mouse gap junction gene connexin29 is highly expressed in sciatic nerve and regulated during brain development. Biol Chem 382(6):973-8
abstractText  A novel mouse gap junction gene, coding for a presumptive protein of 258 amino acids (molecular mass: 28 981 Da), has been designated connexin29. This single copy gene was mapped to distal mouse chromosome 5 and shows 75% sequence identity to a human connexin30.2 sequence in the database. Connexin29 mRNA (4.4 kb) is highly expressed in mouse sciatic nerve and less abundant in spinal cord as well as in adult brain, where it increased 12-fold between day 7 and 14 post partum. Our expression data suggest that the new connexin gene is active in myelin-forming glial cells.
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