| Primary Identifier | MGI:2679684 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 76580 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables ubiquitin protein ligase activity. Acts upstream of or within protein ubiquitination. Located in early endosome and plasma membrane. Part of ubiquitin ligase complex. Is expressed in several structures, including 4th ventricle choroid plexus; genitourinary system; gut; hair follicle; and hemolymphoid system gland. Orthologous to human MIB2 (MIB E3 ubiquitin protein ligase 2). PHENOTYPE: Mice homozygous for a knock-out allele display exencephaly with a variable penetrance that depends on the genetic background. Mice homozygous for a reporter/null allele are viable, fertile and show normal growth, body weight and brain morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
