| Primary Identifier | MGI:1924256 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 77006 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity and ubiquitin-like protein ligase binding activity. Involved in several processes, including cartilage development; negative regulation of IRE1-mediated unfolded protein response; and positive regulation of protein localization to endoplasmic reticulum. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; genitourinary system; immune system; liver and biliary system; and nervous system. Orthologous to human DDRGK1 (DDRGK domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality by E13.5 with impaired embryonic erythropoiesis. Embryos show delayed limb bud condrogenic condensation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
