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Protein Coding Gene : Hint2 histidine triad nucleotide binding protein 2

Primary Identifier  MGI:1916167 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  68917
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable adenosine 5'-monophosphoramidase activity. Acts upstream of or within lipid catabolic process and negative regulation of peptidyl-lysine acetylation. Located in mitochondrion. Is expressed in several structures, including brown fat; liver; lung; metanephros; and spleen. Orthologous to human HINT2 (histidine triad nucleotide binding protein 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit alterations in lipid metabolism, glucose homeostasis, and mitochondrial respiration. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1190005L05 gene,
  • histidine triad nucleotide binding protein 2,
  • Hint2,
  • 1190005L05Rik

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For