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Protein Domain : Suppressor of cytokine signalling 7

Primary Identifier  IPR028423 Type  Family
Short Name  SOCS7
description  SOCS7 is a member of the suppressor of cytokine signaling family of proteins. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation []. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA [].

0 Child Features

0 Parent Features

2 Protein Domain Regions