| First Author | Mogi M | Year | 1995 |
| Journal | Arch Oral Biol | Volume | 40 |
| Issue | 4 | Pages | 361-4 |
| PubMed ID | 7605264 | Mgi Jnum | J:26558 |
| Mgi Id | MGI:74002 | Doi | 10.1016/0003-9969(94)00175-b |
| Citation | Mogi M, et al. (1995) Salivary beta 2-microglobulin in NZB/WF1 mice. Arch Oral Biol 40(4):361-4 |
| abstractText | Unstimulated parotid and submandibular/sublingual saliva from New Zealand black/WF1 (NZB/WF1) mice as collected by microcapillary (1 microliter), and the content of beta 2-microglobulin (beta 2-MG) determined by a sandwich enzyme immunoassay. Salivary beta 2-MG contents of control C57BL/6 and NZB/WF1 mice (45 weeks of age) were 0.68 +/- 0.18 micrograms/ml and 1.42 +/- 0.21 micrograms/ml (mean +/- SD), respectively, from the parotid gland and 0.62 +/- 0.17 micrograms/ml and 1.34 +/- 0.21 microliters/ml, respectively, from the submandibular sublingual glands. However, the concentration of beta 2-MG was not increased in the NZB/WF1 mice at 5 and 20 weeks of age. Saliva from NZB/WF1 mice (45 weeks old) was fractionated by micro two-dimensional gel electrophoresis; it exhibited both qualitative and quantitative changes in protein composition in comparison to the two-dimensional at 5 weeks of age. These observations parallel those in saliva from patients with Sjogren's syndrome. |
