| First Author | Håkansson EM | Year | 1977 |
| Journal | Biochem Genet | Volume | 15 |
| Issue | 1-2 | Pages | 75-85 |
| PubMed ID | 849254 | Mgi Jnum | J:5799 |
| Mgi Id | MGI:54276 | Doi | 10.1007/BF00484549 |
| Citation | Hakansson EM, et al. (1977) Effect of a coat color locus on kidney lysosomal glycosidases in the house mouse. Biochem Genet 15(1-2):75-85 |
| abstractText | Activities of three lysosomal glycosidases, beta-galactosidase, beta-glucuronidase, and N-acetyl-beta-hexosaminidase, have been shown to differ in bf/bf and bf/+ mice. Thus bf/bf mice usually have much higher activities of these enzymes in their kidney cells than bf/+ animals. There seem, however, to be some exceptions to this general pattern, especially for galactosidase of females from the C57BL/6J strain. A likely interpretation of the difference is that the bf locus has pleiotropic effects. An alternative explanation, less likely, is that a gene closely linked to bf is involved. There is also a differential response to dihydrotestosterone in different groups of mice reflected in activity changes of the three enzymes. |
