Primary Identifier | IPR029929 | Type | Family |
Short Name | GAS2 |
description | Growth arrest-specific protein 2 (GAS2) belongs to the GAS2 family, whose members mediate the crosstalk between filamentous actin (F-actin) and microtubules. GAS2 regulates multiple cellular functions including cell cycle, apoptosis and calpain activities [, ]. It is up-regulated in chronic myeloid leukemia cells and required for their growth []. |