| Type | subunit | Description | Homodimer (PubMed:22331899). Component of the circadian core oscillator, which includes the CRY proteins, CLOCK or NPAS2, ARNTL/BMAL1 or ARNTL2/BMAL2, CSNK1D and/or CSNK1E, TIMELESS, and the PER proteins (PubMed:11779462). Interacts directly with TIMELESS (PubMed:10231394, PubMed:9856465). Interacts directly with PER2, PER3, CRY1 and CRY2 (PubMed:10428031, PubMed:10848614, PubMed:11875063, PubMed:14701732, PubMed:16478995, PubMed:24154698). Interacts with ARNTL/BMAL1 and CLOCK (PubMed:16717091, PubMed:24154698). Interacts with GPRASP1 (By similarity). Interacts (phosphorylated) with BTRC and FBXW11; the interactions trigger proteasomal degradation (By similarity). Interacts with NONO and SFPQ (PubMed:22966205). Interacts with WDR5 (By similarity). Interacts with U2AF1L4 (Isoform 3) (PubMed:24837677). Interacts with USP2 (PubMed:23213472). Interacts with HNF4A (By similarity). |
