First Author | Odorizzi G | Year | 1998 |
Journal | Trends Cell Biol | Volume | 8 |
Issue | 7 | Pages | 282-8 |
PubMed ID | 9714600 | Mgi Jnum | J:48443 |
Mgi Id | MGI:1270008 | Doi | 10.1016/s0962-8924(98)01295-1 |
Citation | Odorizzi G, et al. (1998) The AP-3 complex: a coat of many colours. Trends Cell Biol 8(7):282-8 |
abstractText | A new adaptor protein complex, termed AP-3, has recently been identified in mammalian cells, and genetic studies in yeast have revealed a functional role for the AP-3 complex in cargo-selective transport via a new alternative trafficking pathway from the Golgi to the vacuole/lysosome. Here, the authors review what is currently known about the AP-3 complex and discuss recent insight into its function in multicellular organisms that has come from the finding that mutations in AP-3 subunits correspond to classical mutations in Drosophila and mice. |