Primary Identifier | IPR037935 | Type | Family |
Short Name | MAX_gene-associated_protein |
description | MAX gene-associated protein (MGA) is a dual-specificity transcription factor, acting as a repressor or an activator and binding to 5'-AATTTCACACCTAGGTGTGAAATT-3'. MGA regulates genes targeted by MYC-MAX, suppressing transcriptional activation by MYC and inhibiting MYC-dependent cell transformation. MGA binds DNA via a T-Box []. MGA is a component of the MLL1 complex []. |