Primary Identifier | MGI:5661581 | Allele Type | Targeted |
Attribute String | Inducible, Recombinase | Gene | Dcpp1 |
Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NCrl)F1 |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
description | No evidence of ectopic expression in lungs, kidney, pancreas, or ovaries. |
molecularNote | The EGFP-cre/ERT2 (GCE) fragment with an SV40 poly adenylation site and neomycin resistance cassette were inserted immediately downstream of the translational initiation codon ATG. The knock-in construct interrupted coding sequence in exon 2 and placed the GCE gene under the control of the endogenouse regulatory sequences. Flp-mediated recombination removed the selection cassette. No expression of GFP was detected with fluorescence or using antibody to GFP. The fusion cre is expressed in intercalated duct cells of parotid gland and serous cells of sublingual gland. |