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Publication : Sequences and evolution of human and squirrel monkey blue opsin genes.

First Author  Shimmin LC Year  1997
Journal  J Mol Evol Volume  44
Issue  4 Pages  378-82
PubMed ID  9089077 Mgi Jnum  J:39343
Mgi Id  MGI:86726 Doi  10.1007/pl00006157
Citation  Shimmin LC, et al. (1997) Sequences and evolution of human and squirrel monkey blue opsin genes. J Mol Evol 44(4):378-82
abstractText  The sequences of the entire blue opsin gene in the squirrel monkey (Saimiri boliviensis) and the five introns of the human blue opsin gene were obtained. Intron 3 of these genes contains an Alu sequence and intron 4 contains a partial mer13 sequence. A comparison of the squirrel monkey opsin sequence with published mammalian opsin sequences shows that features believed to be functionally critical are all conserved. However, the blue opsin has evolved twice as fast as rhodopsin and is only as conservative as the beta globin, which has evolved at the average rate of mammalian proteins. Interestingly, the interhelical loops are, on average, actually more conservative than the transmembrane alpha helical regions. The introns of the blue opsin gene have evolved at the average rate of introns in primate genes.
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