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Protein Coding Gene : Gal3st1 galactose-3-O-sulfotransferase 1
Primary Identifier  MGI:1858277 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  53897
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables galactosylceramide sulfotransferase activity. Involved in galactosylceramide metabolic process. Acts upstream of or within galactosylceramide biosynthetic process; myelination; and spermatogenesis. Predicted to be located in membrane. Is expressed in brain; future spinal cord; heart ventricle; and spinal cord cervical region. Orthologous to human GAL3ST1 (galactose-3-O-sulfotransferase 1).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit hindlimb weakness and progressive ataxia beginning at six weeks of age. Homozygous males exhibit sterility with a block in spermatogenesis prior to the first meiotic division. [provided by MGI curators]
  • synonyms:
  • galactose-3-O-sulfotransferase 1,
  • cerebroside (3'-phosphoadenylylsulfate:galactosylceramide 3') sulfotransferase,
  • galactosylceramide sulfotransferase,
  • Gal3st1,
  • 3'-phosphoadenylylsulfate-galactosylceramide 3'-sulfotransferase,
  • Cst,
  • GalCer sulfotransferase,
  • Gcst
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1 Transgenic Expressors

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Gene --> Protein-Protein Interactions

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Gene --> Expression annotations

Phenotype

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Disease

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