Primary Identifier | MGI:3771174 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Ppargc1b |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 3 and 4 were replaced with a neo cassette to create a hypomorphic allele. Exons 3 and 4 encode two of three LXXLL motifs. The production of the altered portein product was confirmed by western blot analysis on brown adipose tissue extracts. |